The past few decades have seen a significant increase in research on Osteopathic Manipulative Treatment (OMT). The body of research on OMT has now reached the point where Osteopathy has become an accepted part of the medical literature. As with other common medical procedures (such as surgery, pain procedures or interventional cardiology and radiology), OMT study design has different challenges with blinding, sample size, controls, and physician skill, when compared with pharmaceutical research. Osteopathic manipulation must be evaluated in comparison with research on other procedures in medicine, and it compares favorably in terms of safety, efficacy, and overall study design. The studies linked below cover the use of OMT for low back pain, the discomforts and complications of pregnancy and surgery, its use and safety with children and other topics. These build on the the work of earlier Osteopathic researchers such as Louisa Burns, Wilbur Cole, Irvin Korr, John Denslow, and Viola Frymann, to name a few. Visit the Osteopathic Research Center located at the University of North Texas Health Science Center home of the Texas College of Osteopathic Medicine Visit OSTMED.DR which is a digital library of Osteopathic research from the past 100+ years Research Articles – organized by topic (last updated 09.14.2026)
Back and Neck Pain are some of the most common conditions for which osteopathic treatment is used. These articles study its use in both acute and chronic settings. (see also Obstetrics/Gynecology, Cranial Osteopathy, Gastroenterology)
Pediatrics (See also: Cranial Osteopathy section for additional related studies.) – children respond very well to osteopathic treatment and will benefit from a treatment without side effects. (See also: Lymphatic Function, Obstetrics/Gynecology.)
Obstetrics/Gynecology (See also: Post-Operative Recovery section for additional related studies.) – pregnant patients often experience significant pain which can indicate pelvic problems which could lead to longer deliveries or c-sections. Osteopathic manipulation is a non-pharmaceutical intervention that will not harm the fetus.
Cranial Osteopathy (see also Pediatrics) Further discussion of research into Cranial Osteopathy here
Pulmonology – breathing is dependent on biomechanical factors including diaphragm and rib function, along with lympathic drainage of the lung parenchyma.
Post-Operative Recovery – osteopathy can reduce pain and support recovery, showing its utility in combination with conventional interventions. (See also: Cardiovascular, Gastroenterology.)
Baltazar GA, Betler MP, Akella K, Khatri R, Asaro R, Chendrasekhar A: Effect of osteopathic manipulative treatment on incidence of postoperative ileus and hospital length of stay in general surgical patients. J Am Osteopath Assoc. 2013 Mar;113(3):204-9. PMID: 23485980Gugel MR, Johnston WL. Osteopathic manipulative treatment of a 27-year-old man after anterior cruciate ligament reconstruction. J Am Osteopath Assoc. 2006 Jun. doi: 10.7556/jaoa.2006.106.6.346. PMID: 16790541. O-Yurvati AH, Carnes MS, Clearfield MB, Stoll ST, McConathy WJ: Hemodynamic effects of osteopathic manipulative treatment immediately after coronary artery bypass graft surgery. J Am Osteopath Assoc. 2005 Oct;105(10):475-81. PMID: 16314680Goldstein FJ, Jeck S, Nicholas AS, Berman MJ, Lerario M. Preoperative intravenous morphine sulfate with postoperative osteopathic manipulative treatment reduces patient analgesic use after total abdominal hysterectomy. J Am Osteopath Assoc. 2005 Jun. PMID: 16118354. Licciardone JC, Stoll ST, Cardarelli KM, Gamber RG, Swift JN Jr, Winn WB: A randomized controlled trial of osteopathic manipulative treatment following knee or hip arthroplasty. J Am Osteopath Assoc. 2004 May;104(5):193-202. PMID: 15176518Jarski RW, Loniewski EG, Williams J, Bahu A, Shafinia S, Gibbs K, Muller M. The effectiveness of osteopathic manipulative treatment as complementary therapy following surgery: a prospective, match-controlled outcome study. Altern Ther Health Med. 2000 Sep. PMID: 10979164. Dickey JL. Postoperative osteopathic manipulative management of median sternotomy patients. J Am Osteopath Assoc. 1989 Oct. PMID: 2808026. Roncada G. Osteopathic treatment leads to significantly greater reductions in chronic thoracic pain after CABG surgery: A randomised controlled trial. J Bodyw Mov Ther. 2020 Jul;24(3):202-211. doi: 10.1016/j.jbmt.2020.03.004. Epub 2020 Mar 17. PMID: 32825989.
Lymphatic Function – these basic science articles look at models for lymphatic function and osteopathic approaches to augment drainage. (See also: Cardiovascular.)
Geriatrics (See also: Pulmonology section for additional related studies.) (see also Pulmonology) – older patients often benefit from gentler bodywork approaches available to osteopathic physicians.
Neurology and Rehabilitation – Osteopathy shows much promise in TBIs and other areas of neurology. (See also: Cranial Osteopathy, Pediatrics.)
Other Research (See also: Cranial Osteopathy, Back and Neck Pain, Pediatrics, Pulmonology, Geriatrics, Neurology and Rehabilitation, Lymphatic Function.)